Mount Holyoke's collection of USGS topographic maps (topos) belongs to the Department of Geology and Geography. (Ask at the Dept Office, 3rd floor, Clapp Lab. This collection is distinctive in that it is a historic collection containing older editions of many of the same maps, making possible comparisons over time. Another way to view historic topos is online: Historic USGS Maps of New England (Univ of NH).
The University of Massachusetts-Amherst and Amherst College each maintain a current collection of US Topographic maps. Hampshire College Library has a CD-ROM version of the Massachusetts topos. You can also view current topos online at http://www.topozone.com/.
Scanned images of USGS topos are available via the Internet: